At over 100,000 residents, Lowell is the fourth largest city in Massachusetts. The diverse and historic mill town is located at the intersection of Rte. 495, and Rte. 3, approximately 25 miles north west of Boston, close to the New Hampshire state line. The growth of U. Mass Lowell over recent years, and Lowell's relative afordability, have made Lowell a popular choice for businesses and home buyers alike.